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Publications

McManus Lab publications

 

16

Jan

2018
Dual gene activation and knockout screen reveals directional dependencies in genetic networks Michael Boettcher , Ruilin Tian , James A Blau , Evan Markegard , Ryan T Wagner , David Wu , Xiulei Mo , Anne Biton , Noah Zaitlen , Haian Fu , et.al. Nature biotechnology

02

Nov

2017
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition Matthew J Hangauer , Vasanthi S Viswanathan , Matthew J Ryan , Dhruv Bole , John K Eaton , Alexandre Matov , Jacqueline Galeas , Harshil D Dhruv , Michael E Berens , Stuart L Schreiber , et.al. Nature

21

Oct

2017
CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter Sergio Covarrubias , Elektra K Robinson , Barbara Shapleigh , Apple Vollmers , Sol Katzman , Nicole Hanley , Nicholas Fong , Michael T McManus , Susan Carpenter . The Journal of biological chemistry

04

Jun

2017
Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland D'Juan T Farmer , Sara Nathan , Jennifer K Finley , Kevin Shengyang Yu , Elaine Emmerson , Lauren E Byrnes , Julie B Sneddon , Michael T McManus , Aaron D Tward , Sarah M Knox . Development (Cambridge, England)

18

May

2017
miR-205 is a critical regulator of lacrimal gland development D'Juan T Farmer , Jennifer K Finley , Feeling Y Chen , Estefania Tarifeño-Saldivia , Nancy A McNamara , Sarah M Knox , Michael T McManus . Developmental biology

02

Mar

2017
A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response Zachary Pappalardo , Deeksha Gambhir Chopra , Thomas G Hennings , Hunter Richards , Justin Choe , Katherine Yang , Luc Baeyens , Kenny Ang , Steven Chen , Michelle Arkin , et.al. Diabetes

02

Mar

2017
A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response Zachary Pappalardo , Deeksha Gambhir Chopra , Thomas G Hennings , Hunter Richards , Justin Choe , Katherine Yang , Luc Baeyens , Kenny Ang , Steven Chen , Michelle Arkin , et.al. Diabetes

20

Jan

2017
MicroRNAs in ectodermal appendages D'Juan T Farmer , Michael T McManus . Current opinion in genetics & development

11

Nov

2016
A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity Fumitaka Inoue , Martin Kircher , Beth Martin , Gregory M Cooper , Daniela M Witten , Michael T McManus , Nadav Ahituv , Jay Shendure . Genome research

08

Nov

2016
PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression Dai Horiuchi , Roman Camarda , Alicia Y Zhou , Christina Yau , Olga Momcilovic , Sanjeev Balakrishnan , Alexandra N Corella , Henok Eyob , Kai Kessenbrock , Devon A Lawson , et.al. Nature medicine