Publications

McManus Lab publications

 

31

Jul

2018
A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission Jessica Lee , Zachary Pappalardo , Deeksha Gambhir Chopra , Thomas G Hennings , Ian Vaughn , Christopher Lan , Justin J Choe , Kenny Ang , Steven Chen , Michelle Arkin , et.al. Endocrinology

09

May

2018
Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin Angelino T Tromp , Michiel Van Gent , Pauline Abrial , Amandine Martin , Joris P Jansen , Carla J C De Haas , Kok P M Van Kessel , Bart W Bardoel , Elisabeth Kruse , Emilie Bourdonnay , et.al. Nature microbiology

03

May

2018
Corrigendum: A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity Fumitaka Inoue , Martin Kircher , Beth Martin , Gregory M Cooper , Daniela M Witten , Michael T McManus , Nadav Ahituv , Jay Shendure . Genome research

11

Apr

2018
Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation Wanjing Shang , Yong Jiang , Michael Boettcher , Kang Ding , Marianne Mollenauer , Zhongyi Liu , Xiaofeng Wen , Chang Liu , Piliang Hao , Suwen Zhao , et.al. Proceedings of the National Academy of Sciences of the United States of America

03

Mar

2018
The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output Aydan Bulut-Karslioglu , Trisha A Macrae , Juan A Oses-Prieto , Sergio Covarrubias , Michelle Percharde , Gregory Ku , Aaron Diaz , Michael T McManus , Alma L Burlingame , Miguel Ramalho-Santos . Cell stem cell

24

Feb

2018
Unexplored therapeutic opportunities in the human genome Tudor I Oprea , Cristian G Bologa , Søren Brunak , Allen Campbell , Gregory N Gan , Anna Gaulton , Shawn M Gomez , Rajarshi Guha , Anne Hersey , Jayme Holmes , et.al. Nature reviews. Drug discovery

21

Jan

2018
Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals David Jee , Jr-Shiuan Yang , Sun-Mi Park , D'Juan T Farmer , Jiayu Wen , Timothy Chou , Arthur Chow , Michael T McManus , Michael G Kharas , Eric C Lai . Molecular cell

16

Jan

2018
Dual gene activation and knockout screen reveals directional dependencies in genetic networks Michael Boettcher , Ruilin Tian , James A Blau , Evan Markegard , Ryan T Wagner , David Wu , Xiulei Mo , Anne Biton , Noah Zaitlen , Haian Fu , et.al. Nature biotechnology

02

Nov

2017
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition Matthew J Hangauer , Vasanthi S Viswanathan , Matthew J Ryan , Dhruv Bole , John K Eaton , Alexandre Matov , Jacqueline Galeas , Harshil D Dhruv , Michael E Berens , Stuart L Schreiber , et.al. Nature

21

Oct

2017
CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter Sergio Covarrubias , Elektra K Robinson , Barbara Shapleigh , Apple Vollmers , Sol Katzman , Nicole Hanley , Nicholas Fong , Michael T McManus , Susan Carpenter . The Journal of biological chemistry

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