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A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission
Jessica Lee
,
Zachary Pappalardo
,
Deeksha Gambhir Chopra
,
Thomas G Hennings
,
Ian Vaughn
,
Christopher Lan
,
Justin J Choe
,
Kenny Ang
,
Steven Chen
,
Michelle Arkin
, et.al.
Endocrinology
Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin
Angelino T Tromp
,
Michiel Van Gent
,
Pauline Abrial
,
Amandine Martin
,
Joris P Jansen
,
Carla J C De Haas
,
Kok P M Van Kessel
,
Bart W Bardoel
,
Elisabeth Kruse
,
Emilie Bourdonnay
, et.al.
Nature microbiology
Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation
Wanjing Shang
,
Yong Jiang
,
Michael Boettcher
,
Kang Ding
,
Marianne Mollenauer
,
Zhongyi Liu
,
Xiaofeng Wen
,
Chang Liu
,
Piliang Hao
,
Suwen Zhao
, et.al.
Proceedings of the National Academy of Sciences of the United States of America
Unexplored therapeutic opportunities in the human genome
Tudor I Oprea
,
Cristian G Bologa
,
Søren Brunak
,
Allen Campbell
,
Gregory N Gan
,
Anna Gaulton
,
Shawn M Gomez
,
Rajarshi Guha
,
Anne Hersey
,
Jayme Holmes
, et.al.
Nature reviews. Drug discovery
Dual gene activation and knockout screen reveals directional dependencies in genetic networks
Michael Boettcher
,
Ruilin Tian
,
James A Blau
,
Evan Markegard
,
Ryan T Wagner
,
David Wu
,
Xiulei Mo
,
Anne Biton
,
Noah Zaitlen
,
Haian Fu
, et.al.
Nature biotechnology
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Matthew J Hangauer
,
Vasanthi S Viswanathan
,
Matthew J Ryan
,
Dhruv Bole
,
John K Eaton
,
Alexandre Matov
,
Jacqueline Galeas
,
Harshil D Dhruv
,
Michael E Berens
,
Stuart L Schreiber
, et.al.
Nature