Publications

McManus Lab publications

 

17

May

2024
Decoding gene regulation with CRISPR perturbations Stefan Oberlin , Michael T McManus . Nature biotechnology

20

Feb

2024
Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover Michael J Podolsky , Benjamin Kheyfets , Monika Pandey , Afaq H Beigh , Christopher D Yang , Carlos O Lizama , Ritwik Datta , Liangguang L Lin , Zhihong Wang , Paul J Wolters , et.al. Nature communications

10

Apr

2023
SARS-CoV-2 ORF3A interacts with the Clic-like chloride channel-1 (CLCC1) and triggers an unfolded protein response Hannah N Gruner , Yaohuan Zhang , Kaavian Shariati , Nicholas Yiv , Zicheng Hu , Yuhao Wang , J Fielding Hejtmancik , Michael T McManus , Kevin Tharp , Gregory Ku . PeerJ

22

Mar

2023
Dynamics of Chromatin Accessibility During Hematopoietic Stem Cell Differentiation Into Progressively Lineage-Committed Progeny Eric W Martin , Alessandra Rodriguez Y Baena , Roman E Reggiardo , Atesh K Worthington , Connor S Mattingly , Donna M Poscablo , Jana Krietsch , Michael T McManus , Susan Carpenter , Daniel H Kim , et.al. Stem cells (Dayton, Ohio)

11

Mar

2022
Nucleolar-based Dux repression is essential for embryonic two-cell stage exit Sheila Q Xie , Bryony J Leeke , Chad Whilding , Ryan T Wagner , Ferran Garcia-Llagostera , YiXuan Low , Paul Chammas , Nathan T-F Cheung , Dirk Dormann , Michael T McManus , et.al. Genes & development

24

Jul

2021
miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts Bin Xue , Chen-Hua Chuang , Haydn M Prosser , Cesar Seigi Fuziwara , Claudia Chan , Neil Sahasrabudhe , Maximilian Kühn , Yalei Wu , Jingqi Chen , Anne Biton , et.al. Genes & development

07

Apr

2021
Examining the evidence for extracellular RNA function in mammals Hannah N Gruner , Michael T McManus . Nature reviews. Genetics

30

Dec

2020
High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways Sergio Covarrubias , Apple Cortez Vollmers , Allyson Capili , Michael Boettcher , Aaron Shulkin , Michele Ramos Correa , Haley Halasz , Elektra K Robinson , Laura O'Briain , Christopher Vollmers , et.al. Cell reports

02

Dec

2020
miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling Marcus J Hines , Maryaline Coffre , Tenny Mudianto , Marisella Panduro , Eric J Wigton , Cosmin Tegla , Victoria Osorio-Vasquez , Robin Kageyama , David Benhamou , Oriana Perez , et.al. Cell reports

16

Jul

2020
Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo Laura Bouchareychas , Phat Duong , Sergio Covarrubias , Eric Alsop , Tuan Anh Phu , Allen Chung , Michael Gomes , David Wong , Bessie Meechoovet , Allyson Capili , et.al. Cell reports

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