Yuhao Wang, BS

I completed my undergraduate at the University of Chicago in the laboratory of Dr. Geoffrey Greene. As an undergraduate researcher, I examined the role that microRNAs and nuclear receptors have on triple negative breast cancer survival and metastasis using various mouse and cell line models.

After graduating undergraduate with a B.S. in biological sciences in 2016, I joined the lab of Dr. Ronald Evans at the Salk Institute as a research associate. During my stay at the Salk Institute, I helped two post-docs with their projects. One post-doc was determining the role of FGF1 on lipolysis of adipose tissue, and the other post-doc was studying the role of vitamin D receptor on the epigenetic regulation of pancreatic β cell functions.

After working in the Evans lab for a year, I joined the Biomedical Sciences (BMS) program at UCSF in 2017. In my first year at UCSF, I was awarded the NSF GRFP fellowship. I joined the laboratory of Dr. Michael McManus, and advanced to Ph.D. candidacy in June of 2019. I am currently working on developing an inducible CRISPRi system with the goal of applying this system to study persister cells, or drug tolerant cancer cells. I am interested in exploring the vulnerabilities of persister cells through CRISPR screens and develop new therapeutic approaches to target drug resistance. I am currently working to apply the inducible CRISPRi system to examine hypomorphic phenotypes of essential genes in HEK293T cells.

In my free time I enjoy hiking, finding new restaurants in the city, watching interesting documentaries and videos on YouTube, and playing video games.