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Biblio
] "Next-Generation NAMPT Inhibitors Identified by Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens." Chem Biol 20, no. 11 (2013): 1352-63.
"Partially Penetrant Postnatal Lethality of an Epithelial Specific MicroRNA in a Mouse Knockout." PLoS One 8, no. 10 (2013): e76634.
"Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs." PLoS Genet 9, no. 6 (2013): e1003569.
"The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation." Development 140, no. 16 (2013): 3348-59.
"Renewable RNAi." Nat Biotechnol 31, no. 4 (2013): 319-20.
"A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility." Cell 152, no. 4 (2013): 909-22.
"T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire." J Exp Med 210, no. 2 (2013): 417-32.
"IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2." Science 338, no. 6108 (2012): 818-22.
"Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP." PLoS Genet 8, no. 7 (2012): e1002823.
"Precursor microRNA-programmed silencing complex assembly pathways in mammals." Mol Cell 46, no. 4 (2012): 507-17.
"Research resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome." Mol Endocrinol 26, no. 10 (2012): 1783-92.
"A resource for the conditional ablation of microRNAs in the mouse." Cell Rep 1, no. 4 (2012): 385-91.
"Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing." Nucleic Acids Res 40, no. 18 (2012): 9255-71.
"An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin production." PLoS Genet 8, no. 1 (2012): e1002449.
"Widespread RNA 3'-end oligouridylation in mammals." RNA 18, no. 3 (2012): 394-401.
"The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning." Dev Biol 351, no. 2 (2011): 254-65.
"Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs." PLoS One 6, no. 10 (2011): e26213.
"Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells." Immunity 34, no. 1 (2011): 50-60.
"Analysis of microRNA knockouts in mice." Hum Mol Genet 19, no. R2 (2010): R169-75.
"Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination." Neuron 65, no. 5 (2010): 597-611.
"Chd1 regulates open chromatin and pluripotency of embryonic stem cells." Nature 460, no. 7257 (2009): 863-8.
"Dicer ablation in oligodendrocytes provokes neuronal impairment in mice." Ann Neurol 66, no. 6 (2009): 843-57.
"Dicer is required for proper liver zonation." J Pathol 219, no. 3 (2009): 365-72.
"Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis." Gastroenterology 136, no. 7 (2009): 2304-2315.e1-4.
"Expanded RNA-binding activities of mammalian Argonaute 2." Nucleic Acids Res 37, no. 22 (2009): 7533-45.