Kol Jia

I graduated from the National University of Singapore with a Ph.D. degree and did my thesis work under the supervision of Professors Daniel G. Tenen and Manuel Salto-Tellez in the Cancer Science Institute of Singapore. My thesis work is related to the characterization of the roles of oncofetal protein SALL4 in hepatocellular carcinoma, the major form of liver cancers. After graduation, I continued to characterize the mechanisms of SALL4 in carcinogenesis in Tenen Lab as a research fellow. During the course of my postdoctoral work, I developed immense interest in gene regulation and RNA biology. Therefore, I am expanding my knowledge in gene regulation and RNA biology, particularly the non-coding RNAs, transcription regulation, and chromatin modifications. In my spare time, I like to read, travel, and take pictures.

recent publications

Yong KJ, Li A, Bin Ou W-, Hong CK, Zhao W, Wang F, et al. Targeting SALL4 by entinostat in lung cancer..; 2016. (Oncotarget).
Yong KJ, Basseres DS, Welner RS, Zhang WC, Yang H, Yan B, et al. Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPα expression.. Vol 8.; 2016. (Sci Transl Med; vol 8; no 350).
Li A, Jiao Y, Yong KJ, Wang F, Gao C, Yan B, et al. SALL4 is a new target in endometrial cancer.. Vol 34.; 2015. (Oncogene; vol 34; no 1).
Gao C, Dimitrov T, Yong KJ, Tatetsu H, Jeong H-, Luo HR, et al. Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex.. Vol 121.; 2013. (Blood; vol 121; no 8).
Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, et al. Oncofetal gene SALL4 in aggressive hepatocellular carcinoma.. Vol 368.; 2013. (N Engl J Med; vol 368; no 24).
Yan B, Lim M, Zhou L, Kuick CH, Leong MY, Yong KJ, et al. Identification of MET genomic amplification, protein expression and alternative splice isoforms in neuroblastomas.. Vol 66.; 2013. (J Clin Pathol; vol 66; no 11).