McManus RNA Publications

PUBLICATIONS

Cuellar TL, Davis TH, Nelson PT, Loeb GB, Harfe BD, Ullian E, McManus MT (2008). Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration.
PNAS.

Osokine I, Hsu R, Loeb GB, McManus MT (2008). Unintentional miRNA ablation is a risk factor in gene knockout studies.
PLoS Genetics.

Ku G, McManus MT (2008). Behind the scenes of a small RNA gene-silencing pathway.
Human Gene Therapy.

Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C (2008). Members of the miRNA-200 family regulate olfactory neurogenesis.
Neuron.

Lynn FC, Skewes-Cox P, Kosaka Y, McManus MT, Harfe BD, German MS (2007). MicroRNA expression is required for pancreatic islet cell genesis in the mouse.
Diabetes.

O'Rourke JR, Georges SA, Seay HR, Tapscott SJ, McManus MT, Goldhamer DJ, Swanson MS, Harfe BD (2007). Essential role for Dicer during skeletal muscle development.
Developmental Biology.

Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D (2007). Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2.
Cell.

Harper RW, Xu C, McManus M, Heidersbach A, Eiserich JP (2006). Duox2 exhibits potent heme peroxidase activity in human respiratory tract epithelium.
FEBS Letters.

Heidersbach A, Gasper-Maia, McManus MT, Ramalho-Santos M (2006). RNA interference in embryonic stem cells and the prospects for future therapies.
Gene Therapy.

Harris KS, Zhang Z, McManus MT, Harfe BD, Sun X (2005). Dicer function is essential for lung epithelium morphogenesis. PNAS.

Cuellar TL, McManus MT (2005). microRNAs and endocrine biology. J. Endocrinology.

Hornstein E, Mansfield JH, Yekta S, Kuang-Hsien H, Harfe BD, McManus MT, Baskerville S, Bartel DP, Tabin CJ (2005). The microRNA miR196 acts upstream
of Hoxb8 and Shh in limb development. Nature.

Morris JP 4th, McManus MT (2005). Slowing down the Ras lane: miRNAs as tumor suppressors? Sci STKE.

Hong JH, Hwang ES, McManus MT, Amsterdam A, Tian Y., Klamukova R, Mueller E, Benjamin T, Spiegelman BM, Sharp PA, Hopkins N, Yaffe MB (2005). TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science.

Harfe BD, McManus, MT, Mansfield JH, Hornstein E, Tabin CJ (2005). The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. PNAS.

McManus, MT (2004). Small RNAs in Immunity. Immunity.

Mansfield JH, Harfe B, Nissen, R, Obenaur J, Srineel J, Chaudhuri A, Farzan-Kashani R, Zuker M, Pasquinelli AE, Ruvkyun G, Sharp PA, Tabin CJ, McManus MT (2004). microRNA-responsive transgenes reveal Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nature Genetics.

Ventura A, Meissner A, Dillon CP, McManus MT, Sharp PA, Van Parijs, L, Jaenisch R, Jacks, T (2004). A Cre-lox based method for conditional RNA interference in mice and cells. PNAS.

McManus MT (2003). MicroRNAs in Cancer. Seminars in Cancer Biology.

Ge Q, McManus MT, Nguyen T, Sharp PA, Eisen HE, and Chen J. (2003) RNA interference of Influenza virus production by both mRNA-specific and virus-specific mechanisms. PNAS.

Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, Zhang M, McManus MT, Gertler FB, Scott ML, Van Parijs L. (2003). A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nature Genetics.

McManus MT, Haines BB, Dillon C, Whitehurst CE, van Parijs L, Chen J. and Sharp PA (2002). siRNA-mediated gene silencing in T-lymphocytes. Immunology.

McManus MT and Conklin D, (2002). Small hairpin RNA-mediated silencing of mammalian gene expression, RNAi: A guide to gene silencing, book chapter, CSH press.

McManus MT and Sharp PA (2002). Gene silencing in mammals by siRNAs. Nature Reviews Genetics.

Zhihong C, Indjeian VB, McManus MT, Wang L, and Dynlacht BD (2002). A novel, cell cycle-dependent centriolar CDK substrate regulates centrosome duplication in human cells. Dev. Cell.

McManus MT, Petersen, CP, Haines, B, Chen, J. and Sharp PA (2002). Gene Silencing using micro-RNA designed hairpins. RNA.

McManus MT, Shimamura MS, Grams J, and Hajduk SL (2001). Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei. RNA.

Grams J., McManus MT, Hajduk SL (2000). Processing of polycistronic guide RNAs is associated with RNA editing complexes in Trypanosoma brucei. EMBO J.

McManus MT, Adler BK, Pollard VW, and SL Hajduk (1998). Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA. Mol. Cell. Bio.