Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance..; 2016. (Mol Cancer Res).


Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, et al. Epigenetic and transcriptional determinants of the human breast.. Vol 6.; 2015. (Nat Commun; vol 6).
Patton JG, Franklin JL, Weaver AM, Vickers K, Zhang B, Coffey RJ, et al. Biogenesis, delivery, and function of extracellular RNA.. Vol 4.; 2015. (J Extracell Vesicles; vol 4).
Khan IS, Park CY, Mavropoulos A, Shariat N, Pollack JL, Barczak AJ, et al. Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells.. Vol 10.; 2015. (PLoS ONE; vol 10; no 8).
Boettcher M, McManus MT. Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR.. Vol 58.; 2015. (Mol Cell; vol 58; no 4).
Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, et al. Integrative analysis of 111 reference human epigenomes.. Vol 518.; 2015. (Nature; vol 518; no 7539).


Morris JP, Greer R, Russ HA, von Figura G, Kim GE, Busch A, et al. Dicer Regulates Differentiation and Viability during Mouse Pancreatic Cancer Initiation.. Vol 9.; 2014. (PLoS ONE; vol 9; no 5).
Qin H, Diaz A, Blouin L, Lebbink RJ, Patena W, Tanbun P, et al. Systematic Identification of Barriers to Human iPSC Generation.. Vol 158.; 2014. (Cell; vol 158; no 2).
Zhao W, Pollack JL, Blagev DP, Zaitlen N, McManus MT, Erle DJ. Massively parallel functional annotation of 3' untranslated regions..; 2014. (Nat Biotechnol).
Hangauer MJ, Carpenter S, McManus MT. Discovering the complexity of the metazoan transcriptome.. Vol 15.; 2014. (Genome Biol; vol 15; no 4).
van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation.. Vol 5.; 2014. (Nat Commun; vol 5).


Blau JA, McManus MT. Renewable RNAi. Nat Biotechnol. 2013;31(4):319-20.
Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, et al. The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development. 2013;140(16):3348-59.
Farmer D', Shariat N, Park CY, Liu HJ, Mavropoulos A, McManus MT. Partially Penetrant Postnatal Lethality of an Epithelial Specific MicroRNA in a Mouse Knockout. PLoS ONE. 2013;8(10):e76634.
Bronevetsky Y, Villarino AV, Eisley CJ, Barbeau R, Barczak AJ, Heinz GA, et al. T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire. J Exp Med. 2013;210(2):417-32.
Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, et al. Next-Generation NAMPT Inhibitors Identified by Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens. Chem Biol. 2013;20(11):1352-63.
Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, et al. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 2013;152(4):909-22.


Ku GM, Kim H, Vaughn IW, Hangauer MJ, Oh CM, German MS, et al. Research resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome.. Vol 26.; 2012. (Mol Endocrinol; vol 26; no 10).
Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, et al. Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012;8(7):e1002823.
Ku GM, Pappalardo Z, Luo CC, German MS, McManus MT. An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin production. PLoS Genet. 2012;8(1):e1002449.
Ku GM, Kim H, Vaughn IW, Hangauer MJ, Oh CM, German MS, et al. Research resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome. Mol Endocrinol. 2012;26(10):1783-92.
Choi YS, Patena W, Leavitt AD, McManus MT. Widespread RNA 3'-end oligouridylation in mammals. RNA. 2012;18(3):394-401.
Upton J-, Wang L, Han D, Wang ES, Huskey NE, Lim L, et al. IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. Science. 2012;338(6108):818-22.
Liu X, Jin D-, McManus MT, Mourelatos Z. Precursor microRNA-programmed silencing complex assembly pathways in mammals. Mol Cell. 2012;46(4):507-17.
Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, et al. A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 2012;1(4):385-91.
Dallas A, Ilves H, Ge Q, Kumar P, Shorenstein J, Kazakov SA, et al. Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing. Nucleic Acids Res. 2012;40(18):9255-71.


Villarino AV, Katzman SD, Gallo E, Miller O, Jiang S, McManus MT, et al. Posttranscriptional silencing of effector cytokine mRNA underlies the anergic phenotype of self-reactive T cells. Immunity. 2011;34(1):50-60.
Zhang Z, O'Rourke JR, McManus MT, Lewandoski M, Harfe BD, Sun X. The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning. Dev Biol. 2011;351(2):254-65.
Lebbink RJ, Lowe M, Chan T, Khine H, Wang X, McManus MT. Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs. PLoS ONE. 2011;6(10):e26213.


Dugas JC, Cuellar TL, Scholze A, Ason B, Ibrahim A, Emery B, et al. Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron. 2010;65(5):597-611.
Park CY, Choi YS, McManus MT. Analysis of microRNA knockouts in mice. Hum Mol Genet. 2010;19(R2):R169-75.


Shin D, Shin J-, McManus MT, Ptácek LJ, Fu Y-. Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann Neurol. 2009;66(6):843-57.
Ruggiero T, Tarifeño-Saldivia E, De Santa F, Zupo S, Harfe BD, McManus MT, et al. LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J. 2009;23(9):2898-908.
Papaioannou MD, Pitetti J-, Ro S, Park C, Aubry F, Schaad O, et al. Sertoli cell Dicer is essential for spermatogenesis in mice. Dev Biol. 2009;326(1):250-9.
Bassik MC, Lebbink RJ, L Churchman S, Ingolia NT, Patena W, Leproust EM, et al. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat Methods. 2009;6(6):443-5.
Pastorelli LM, Wells S, Fray M, Smith A, Hough T, Harfe BD, et al. Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract. Mamm Genome. 2009;20(3):140-51.
Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, et al. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature. 2009;460(7257):863-8.
Sekine S, Ogawa R, Ito R, Hiraoka N, McManus MT, Kanai Y, et al. Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis. Gastroenterology. 2009;136(7):2304-2315.e1-4.
Sekine S, Ogawa R, McManus MT, Kanai Y, Hebrok M. Dicer is required for proper liver zonation. J Pathol. 2009;219(3):365-72.
Soukup GA, Fritzsch B, Pierce ML, Weston MD, Jahan I, McManus MT, et al. Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice. Dev Biol. 2009;328(2):328-41.
Tan GS, Garchow BG, Liu X, Yeung J, Morris JP, Cuellar TL, et al. Expanded RNA-binding activities of mammalian Argonaute 2. Nucleic Acids Res. 2009;37(22):7533-45.
Huang T-, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A, et al. Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. J Biol Chem. 2009;284(27):18515-24.


Davis TH, Cuellar TL, Koch SM, Barker AJ, Harfe BD, McManus MT, et al. Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci. 2008;28(17):4322-30.
Ku G, McManus MT. Behind the scenes of a small RNA gene-silencing pathway. Hum Gene Ther. 2008;19(1):17-26.
Osokine I, Hsu R, Loeb GB, McManus MT. Unintentional miRNA ablation is a risk factor in gene knockout studies: a short report. PLoS Genet. 2008;4(2):e34.
Maatouk DM, Loveland KL, McManus MT, Moore K, Harfe BD. Dicer1 is required for differentiation of the mouse male germline. Biol Reprod. 2008;79(4):696-703.
Zhou X, Jeker LT, Fife BT, Zhu S, Anderson MS, McManus MT, et al. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med. 2008;205(9):1983-91.
Choi PS, Zakhary L, Choi W-, Caron S, Alvarez-Saavedra M, Miska EA, et al. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008;57(1):41-55.
Cuellar TL, Davis TH, Nelson PT, Loeb GB, Harfe BD, Ullian E, et al. Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci USA. 2008;105(14):5614-9.
Harvey SJ, Jarad G, Cunningham J, Goldberg S, Schermer B, Harfe BD, et al. Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol. 2008;19(11):2150-8.
Damiani D, Alexander JJ, O'Rourke JR, McManus MT, Jadhav AP, Cepko CL, et al. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci. 2008;28(19):4878-87.


Crittenden JR, Heidersbach A, McManus MT. Lentiviral strategies for RNAi knockdown of neuronal genes. Curr Protoc Neurosci. 2007;Chapter 5:Unit 5.26.
O'Rourke JR, Georges SA, Seay HR, Tapscott SJ, McManus MT, Goldhamer DJ, et al. Essential role for Dicer during skeletal muscle development. Dev Biol. 2007;311(2):359-68.
Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell. 2007;129(2):303-17.
Lynn FC, Skewes-Cox P, Kosaka Y, McManus MT, Harfe BD, German MS. MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes. 2007;56(12):2938-45.


Harris KS, Zhang Z, McManus MT, Harfe BD, Sun X. Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci USA. 2006;103(7):2208-13.
Heidersbach A, Gaspar-Maia A, McManus MT, Ramalho-Santos M. RNA interference in embryonic stem cells and the prospects for future therapies. Gene Ther. 2006;13(6):478-86.
Harper RW, Xu C, McManus MT, Heidersbach A, Eiserich JP. Duox2 exhibits potent heme peroxidase activity in human respiratory tract epithelium. FEBS Lett. 2006;580(22):5150-4.


Cuellar TL, McManus MT. MicroRNAs and endocrine biology. J Endocrinol. 2005;187(3):327-32.
Harfe BD, McManus MT, Mansfield JH, Hornstein E, Tabin CJ. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci USA. 2005;102(31):10898-903.
Hong J-, Hwang ES, McManus MT, Amsterdam A, Tian Y, Kalmukova R, et al. TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science. 2005;309(5737):1074-8.
Morris JP, McManus MT. Slowing down the Ras lane: miRNAs as tumor suppressors? Sci STKE. 2005;2005(297):pe41.
Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT, et al. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature. 2005;438(7068):671-4.


Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A, et al. MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet. 2004;36(10):1079-83.
McManus MT. Small RNAs and immunity. Immunity. 2004;21(6):747-56.
Ventura A, Meissner A, Dillon CP, McManus MT, Sharp PA, Van Parijs L, et al. Cre-lox-regulated conditional RNA interference from transgenes. Proc Natl Acad Sci USA. 2004;101(28):10380-5.


Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet. 2003;33(3):401-6.
Ge Q, McManus MT, Nguyen T, Shen C-, Sharp PA, Eisen HN, et al. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci USA. 2003;100(5):2718-23.
McManus MT. MicroRNAs and cancer. Semin Cancer Biol. 2003;13(4):253-8.


McManus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nat Rev Genet. 2002;3(10):737-47.
Chen Z, Indjeian VB, McManus MT, Wang L, Dynlacht BD. CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells. Dev Cell. 2002;3(3):339-50.
McManus MT, Haines BB, Dillon CP, Whitehurst CE, Van Parijs L, Chen J, et al. Small interfering RNA-mediated gene silencing in T lymphocytes. J Immunol. 2002;169(10):5754-60.
McManus MT, Petersen CP, Haines BB, Chen J, Sharp PA. Gene silencing using micro-RNA designed hairpins. RNA. 2002;8(6):842-50.


McManus MT, Shimamura M, Grams J, Hajduk SL. Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei. RNA. 2001;7(2):167-75.


McManus MT, Adler BK, Pollard VW, Hajduk SL. Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA. Mol Cell Biol. 2000;20(3):883-91.


Sabatini RS, Adler BK, Madison-Antenucci S, McManus MT, Hajduk SL. Biochemical methods for analysis of kinetoplastid RNA editing. Methods. 1998;15(1):15-26.


Hajduk SL, Adler B, Madison-Antenucci S, McManus MT, Sabatini R. Insertional and deletional RNA editing in trypanosome mitochondria. Nucleic Acids Symp Ser. 1997;(36):15-8.